Selenium And Free Radical Status In Patients With Acute Coronary Syndrome

Yuldashov Farrux Shuxratovich; Xaydarov Jaxongir G’ulom o’g’li

Authors

Yuldashov Farrux Shuxratovich Assistant, Department of Internal Diseases in Family Medicine No. 1 and Fundamentals of Preventive Medicine, Tashkent State Medical University, Tashkent, 100109, Uzbekistan
Xaydarov Jaxongir G’ulom o’g’li Assistant, Department of Internal Diseases in Family Medicine No. 1 and Fundamentals of Preventive Medicine, Tashkent State Medical University, Tashkent, 100109, Uzbekistan

Keywords:

Selenium, free radical oxidation

Abstract

Acute coronary syndrome (ACS) remains a major cause of cardiovascular morbidity in Uzbekistan. This prospective study evaluated serum selenium levels and free radical status in 122 patients with ACS variants (new-onset angina, unstable angina, non-Q-wave myocardial infarction) admitted to the Republican Specialized Scientific-Practical Medical Center of Cardiology in Tashkent. Selenium levels were suboptimal (mean 61.6 ± 1.6 µg/L), with evidence of intensified free radical oxidation and reduced antioxidant protection. Negative correlations existed between selenium and chemiluminescence parameters. Results support selenium status monitoring and potential organic selenium supplementation to mitigate oxidative stress and improve prognosis.

References

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Selenium And Free Radical Status In Patients With Acute Coronary Syndrome

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